AbMask™ & SynTac™ Platform
Conditional Activation or Co-stimulation T-Cell Engager
PART 1
AbMask™ Pro-TCE Platform
Masking CD3 before getting exposed in the TME, enables manageble peripheral T cell activation while maximizing intratumoral T cell infiltration, activation, persistence and tumor killing.
PART 2
SynTac™ Co-stimulatory TCE Platform
Incoporating CD2 adhesion and costim into TCE design enables optimal T cell activation and persistence, thus more robust tumor-killing while achiving manageble CRS risk.